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Old 26th August 2019, 03:02 AM   #2
McHrozni
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Join Date: Jun 2009
Posts: 11,919
Originally Posted by casebro View Post
Natural Killer cell donation for the sake of a cancer patient relative. Anybody here know the procedure? Looks like they start with a plasma extraction, but do they put the remains of the plasma back in?
Yes. Donating blood cells (and plasma) is a common medical procedure, the blood is drawn in a continuous system, the cells separated from plasma, the relevant cell layer is removed and the rest of the blood put back into patient.

It all sounds scary, but it is not. You would be donating a buffy coat:

https://upload.wikimedia.org/wikiped...ion-scheme.png

The blood is commonly processed after donation, you almost never recieve a donation of full blood. It is usually erithrocytes plus saline, we use plasma for other patients who need fresh frozen plasma, such as hemophiliacs. The reason why your blood would be put back in you is because there are very few leukocytes in blood as compared to other fractions and only a few percent of them would be NK cells.

This is done through apheresis:
https://www.researchgate.net/profile...FPP-plasma.png

Quote:
And would diabetes, kidneys, BP(meds) preclude a donor?
Probably not, but ask your doctor all the same.

McHrozni
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Last edited by McHrozni; 26th August 2019 at 03:04 AM.
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