Originally Posted by casebro
Although the machine itself is a bit complex, the donor's role is very simple and pretty much pain free. They put iv's in the donor, the needle pricks being the only things that might conceivably be considered painful. Then they collect the cells and return the plasma to the donor simultaneously as they sit in a chair for 6 to 8 hours. The donor doesn't feel anything except boredom. They never lack for plasma.
I am vey sorry to hear of your brother's situation; I wish him the best!