Originally Posted by
Puppycow
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Both patients and clinicians were desperate.
Enter hydroxychloroquine. On March 16, 2020, a study on use of hydroxychloroquine in patients with SARS-CoV-2 was “published” (online via YouTube) by Gautret et al6 (followed 4 days later as a preprint in the International Journal of Antimicrobial Agents) and purportedly demonstrated “a rapid and effective speeding up of their healing process, and a sharp decrease in the amount of time they remained contagious.”. This open-label, nonrandomized study included only 36 hospitalized patients...
However, the politicization of the treatment was a more important factor in promoting interest in use of this drug. On April 4, the US president, “speaking on gut instinct,” promoted the drug as a potential treatment and authorized the US government to purchase and stockpile 29 million pills of hydroxychloroquine for use by patients with COVID-19...
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US health officials, such as members of the Coronavirus Task Force, leaders from the National Institutes of Health, and officers of physician organizations and societies, who resisted being forced to promote the politically motivated use of hydroxychloroquine were correct and should be recognized for their steadfast commitment to science...
The clear, unambiguous, and compelling lesson from the hydroxychloroquine story for the medical community and the public is that science and politics do not mix. Science, by definition, requires diligence and an honest assessment of findings; politics not so much. The number of articles in the peer-reviewed literature over the last several months that have consistently and convincingly demonstrated the lack of efficacy of a highly hyped “cure” for COVID-19 represent the consequence of the irresponsible infusion of politics into the world of scientific evidence and discourse.