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Old 23rd November 2021, 02:38 PM   #6
Louden Wilde
Critical Thinker
Join Date: Oct 2020
Location: NYC
Posts: 380
Originally Posted by Planigale View Post
Complete androgen insensitivity (1: 20,000 - 1:100,000 live births) causes an XY (genotype male) to be born with a female phenotype. This is the most common form of 'intersex'.
The activists who push the 'sex is a spectrum' idea or similar often include CAH (congenital adrenal hyperplasia) in this group - only potentially applicable as a DSD to females. But it's more frequent - 1 in 8,000 to 1 in 29,000. I see the causal variants a lot in my job (clinical genetics in NYC). I'm surprised that those activists don't try and include cystic fibrosis (more common still) since CF males typically lack a vas deferens.
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