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Old 27th April 2019, 07:42 AM   #1
wasapi
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Hope. The latest on ketamine.

Ketamine seems to be the new, evolving treatment for depression.

https://www.thelancet.com/journals/l...392-2/fulltext

About 2 years ago, my doctor gave me a ketamine infusion for chronic pain and depression. I only had one because of the price. But what I noticed right away a great relief of depression.

The treatment itself is almost hallucinatory, with a rush of positivity and peace, a floating sensation, and I couldn't stop smiling.

In the past 2 years since my treatment, I am hearing more and more about ketamine; approval from FDA, highly recommended by many in the medical field, used for intense, chronic pain. My sister recently started using a ketamine nasal spray for her unbearable pain. She says the drug has prevented her from being bedridden or in the hospital, and has her no longer thinking about suicide.

The issue, for me, is the expense.

I would be interested on opinions. Thanks.


I'm interested
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Old 27th April 2019, 07:51 AM   #2
kellyb
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I think it's great. I think the "war on drugs" has resulted in nonsense restrictions on pharmaceuticals.

They're also doing MDMA trials for all sorts of things which look very promising.
For example: http://www.prati.org.il/wp-content/u...2019/01/23.pdf
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Old 27th April 2019, 08:17 AM   #3
The Great Zaganza
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Don't travel to the UK with Ketamine.
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Old 27th April 2019, 09:00 AM   #4
dann
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Originally Posted by wasapi View Post
The treatment itself is almost hallucinatory, with a rush of positivity and peace, a floating sensation, and I couldn't stop smiling.
The contraindications and side effects seem to be considerable.
Also, judged by your description, you might consider lowering the dose, which might also make it cheaper. You could probably do without the near-hallucinations, the rush (!) and the floating sensation, and the inability to stop smiling doesn't really sound great. You'd probably be laid off if you worked in a funeral parlor!
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Old 27th April 2019, 12:22 PM   #5
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Couple of years ago I ended up in the ER with a dislocated jaw. Conventional methods didn’t work so they gave me Ketamine to put me out while they got more violent with my jaw to relocate it.

I went down the K-hole.

I will not do that again.
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Old 27th April 2019, 12:42 PM   #6
wasapi
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Smile

Originally Posted by dann View Post
The contraindications and side effects seem to be considerable.
Also, judged by your description, you might consider lowering the dose, which might also make it cheaper. You could probably do without the near-hallucinations, the rush (!) and the floating sensation, and the inability to stop smiling doesn't really sound great. You'd probably be laid off if you worked in a funeral parlor!
What, you have something against smiling?
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Old 27th April 2019, 12:57 PM   #7
dann
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Yes, when somebody can't stop, I do.
I always suspect that they're trying to persuade me to join a cult!
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"Stupidity renders itself invisible by assuming very large proportions. Completely unreasonable claims are irrefutable. Ni-en-leh pointed out that a philosopher might get into trouble by claiming that two times two makes five, but he does not risk much by claiming that two times two makes shoe polish." B. Brecht
"The abolition of religion as the illusory happiness of the people is required for their real happiness. The demand to give up the illusion about its condition is the demand to give up a condition which needs illusions." K. Marx
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Old 27th April 2019, 01:16 PM   #8
Captain_Swoop
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Then there is it's effects on your bladder to consider.
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Old 28th April 2019, 02:26 PM   #9
Manger Douse
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(Let's all go to a ) Ketamine Party:

https://www.youtube.com/watch?v=otjY8fW0p0E

(what am I doing wrong with the youtube embeds? - using yt - /yt and get the correct window but a streaming error?)

Last edited by Manger Douse; 28th April 2019 at 02:28 PM.
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Old 28th April 2019, 03:13 PM   #10
Captain_Swoop
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it should be yt in [] brackets then just the bit of the address after the = sign then /yt in [] brackets to close it off
so yours would be the otjY8fW0p0E part of the address like this

YouTube Video This video is not hosted by the ISF. The ISF can not be held responsible for the suitability or legality of this material. By clicking the link below you agree to view content from an external website.
I AGREE
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Old 3rd May 2019, 11:49 PM   #11
novaphile
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What Captain_Swoop said.

Like this:

Code:
[yt]otjY8fW0p0E[/yt]
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Old 7th May 2019, 08:42 PM   #12
bigred
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Quote:
In the past 2 years since my treatment, I am hearing more and more about ketamine; approval from FDA,
Esketamine was approved, but it's not the same thing.

Quote:
highly recommended by many in the medical field, used for intense, chronic pain.
Sounds rather vague, esp "in the medical field."

I'm not trying to knock it, just advising caution.
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Old 7th May 2019, 08:53 PM   #13
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There are always trade-offs in using medications. The prevailing paradigm is that the use of a certain drug is balanced against the probable and/or possible negative side effects.

The use of Ketamine under certain specific conditions by paramedic staff in my area (BC, Canada) has been common for a number of years. There is a move to get it used in more situations involving severe pain in emergency transport.
https://globalnews.ca/news/5206640/ketamine-paramedics/
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Last edited by rockinkt; 7th May 2019 at 09:02 PM. Reason: edit grammar and sentence structure
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Old 7th May 2019, 09:17 PM   #14
Puppycow
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Originally Posted by wasapi View Post
The treatment itself is almost hallucinatory, with a rush of positivity and peace, a floating sensation, and I couldn't stop smiling.
Originally Posted by dann View Post
The contraindications and side effects seem to be considerable.
Also, judged by your description, you might consider lowering the dose, which might also make it cheaper. You could probably do without the near-hallucinations, the rush (!) and the floating sensation, and the inability to stop smiling doesn't really sound great. You'd probably be laid off if you worked in a funeral parlor!
The first high is always the best one, I hear.

I've never been addicted to opioids myself (never tried them), but nicotine, alcohol and pot. I'm guessing that I would be instantly addicted by "a rush of positivity and peace". Who wouldn't?
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Old 14th May 2019, 05:22 PM   #15
cosmicaug
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Originally Posted by bigred View Post
Esketamine was approved, but it's not the same thing.
It's essentially the same thing. The main difference is that by using only one of the ketamine enantiomers they can charge about a couple of orders of magnitude more for the pharmaceutical (I forget the approximate factor but I calculated it once and it's huge).
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